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fjfaase 2 days ago [-]
In mouse by artificially increasing it. I guess there are lots of proteins that do this when at higher than normal levels.
This says nothing about the effects of artificially reducing levels in humans.
VerifiedReports 2 days ago [-]
The article neglects to say HOW they "reduced FTL1."
amluto 2 days ago [-]
If you click the link to the actual paper, you’ll find:
> Next, we sought to explore the potential benefit of targeting the age-related increase of FTL1 in the hippocampus of aged mice. We performed targeted stereotaxic injections of a high-titer virus encoding shRNA sequences targeting either Ftl1 or luciferase control into the CA1 and dentate gyrus hippocampal regions of aged mice (Fig. 3b and Extended Data Fig. 5a,b).
There are lots of bio research techniques that can be applied to mice that you wouldn’t necessarily want to do to yourself…
subscribed 14 hours ago [-]
>> "luciferase"....
<3
Oras 2 days ago [-]
Also focusing on memory and metabolism, I thought it’s about aging in general such as muscles and mobility
davydm 2 days ago [-]
Claude reckons by combatting spare iron in the blood (ftl1 is apparently iron-based), so iron chelators like green tea after every meal.
This says nothing about the effects of artificially reducing levels in humans.
> Next, we sought to explore the potential benefit of targeting the age-related increase of FTL1 in the hippocampus of aged mice. We performed targeted stereotaxic injections of a high-titer virus encoding shRNA sequences targeting either Ftl1 or luciferase control into the CA1 and dentate gyrus hippocampal regions of aged mice (Fig. 3b and Extended Data Fig. 5a,b).
There are lots of bio research techniques that can be applied to mice that you wouldn’t necessarily want to do to yourself…
<3